MBRS-62. REPRESSIVE CHROMATIN REMODELERS IN SHH-DRIVEN MEDULLOBLASTOMA

Medulloblastoma (MB) is a malignant pediatric brain tumor characterized by poor neuronal differentiation. The RE1 Silencing Transcription Factor (REST), which negatively regulates neurogenesis by promoting repressive chromatin remodeling via epigenetic modifications, is overexpressed in human MBs. A...

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Udgivet i:Neuro Oncol
Main Authors: Tao, Rong-Hua, Dobson, Tara, Maegawa, Shinji, Swaminathan, Jyothismathi, Shaik, Shavali, Taylor, Pete, Kennis, Bridget, Qi, Lin, Khatua, Soumen, Goldman, Stewart, Lulla, Rishi, Fangusaro, Jason, MacDonald, Tobey, Li, Xiao-Nan, Hawkins, Cynthia, Rajaram, Veena, Gopalakrishnan, Vidya
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012124/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.506
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