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LGG-31. SUSTAINED OBJECTIVE RESPONSE TO DABRAFENIB THERAPY ACROSS DIFFERENT BRAIN HISTOLOGIES HARBOURING BRAF V600E ACTIVATING MUTATION
Paediatric low-grade gliomas are the most common brain tumours in children. They are characterized by alterations of the Ras/MAPK pathway. Gliomas harbouring BRAF activating mutations were repeatedly shown to respond to BRAF inhibition. We present our experience with dabrafenib monotherapy in four p...
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| Izdano u: | Neuro Oncol |
|---|---|
| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6012012/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.372 |
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