LGG-31. SUSTAINED OBJECTIVE RESPONSE TO DABRAFENIB THERAPY ACROSS DIFFERENT BRAIN HISTOLOGIES HARBOURING BRAF V600E ACTIVATING MUTATION

Paediatric low-grade gliomas are the most common brain tumours in children. They are characterized by alterations of the Ras/MAPK pathway. Gliomas harbouring BRAF activating mutations were repeatedly shown to respond to BRAF inhibition. We present our experience with dabrafenib monotherapy in four p...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Sumerauer, David, Krskova, Lenka, Kyncl, Martin, Zapotocky, Michal, Kuklova, Adela, Zamecnik, Josef, Ondrova, Barbora, Stary, Jan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012012/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.372
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