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DIPG-62. CARBOPLATIN SYNERGIZES WITH BCL-2 INHIBITOR TO POTENTIATE KILLING OF DIPG CELLS

The only proven effective therapy for diffuse intrinsic pontine glioma is radiation, and this modality only extends life. Carboplatin is being explored for convection-enhanced delivery in DIPG patients, with the hypothesis being that high doses of carboplatin can effectively kill DIPG cells. The BH3...

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Publicado en:Neuro Oncol
Autores principales: Shah, Smit, Rubens, Jeffrey, Eberhart, Charles, Raabe, Eric
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012003/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.155
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