NFM-10. TARGETING NuRD AND KAT7 FOR EPIGENOME MODIFICATION IN NEUROFIBROMATOSIS1 ASSOCIATED MALIGNANT PERIPHERAL NERVE SHEATH TUMORS

Neurofibromatosis type 1 (NF1) is common, occurring in 1/3000 live births, and results in skin pigmentation and the growth of tumors along nerves in the skin, brain, and other parts of the body. Loss of polycomb repressive complex 2 (PRC2) has been implicated in the tumorigenesis of Schwann cells (S...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Mayanil, Chandra, Khan, Mariam, Mohanty, Vineet, Kumar, Raj, Xi, Guifa, Ichi, Shunsuke, Singh, Bal Ram, Mania-Farnell, Barbara, Tomita, Tadanori
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6011958/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.518
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