CRAN-17. TUMOUR COMPARTMENT TRANSCRIPTOMICS DEMONSTRATE THE ACTIVATION OF INFLAMMATORY AND ODONTOGENIC PROGRAMMES IN HUMAN ADAMANTINOMATOUS CRANIOPHARYNGIOMA AND IDENTIFY NOVEL THERAPEUTIC TARGETS

Adamantinomatous Craniopharyngiomas (ACPs) are challenging sellar region tumours, known to be characterised by mutations in CTNNB1. ACPs are often histologically complex, with different morphological cell types and surrounded by reactive glial tissue. Murine models, generated through activating β-ca...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Apps, John, Guiho, Romaine, Hong, Ying, Hargrave, Darren, Brogan, Paul, Jacques, Thomas, Martinez-Barbera, Juan Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6011945/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.053
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