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MBRS-47. ESTABLISHMENT OF A 3D SPHEROID-BASED MODEL OF MEDULLOBLASTOMA THAT RECAPITULATES TUMOUR GROWTH, DRUG RESPONSE AND MIGRATION

Medulloblastoma is the most common malignant brain tumour, accounting for 15-20% of all childhood brain tumours. Traditional two-dimensional (2D) cell culture fails to recapitulate the multi-dimensional growth and complex microenvironment observed in patient tumours and hence is limited in its abili...

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Publicado en:Neuro Oncol
Autores principales: Roper, Sophie J, Scotting, Paul J, Coyle, Beth
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6011893/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.492
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