MBRS-37. IN VITRO MODELLING OF TUMOUR EVOLUTION AND RADIOTHERAPY RESISTANCE IN MEDULLOBLASTOMA

Medulloblastoma relapse occurs in 30-40% of patients, is almost universally fatal and accounts for ~10% of childhood cancer deaths. Acquisition of combined MYC/MYCN and TP53 defects occurs in 30% of recurrences following standard-upfront-treatment. Therapy-related selection pressure plays a role in...

詳細記述

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書誌詳細
出版年:Neuro Oncol
主要な著者: Richardson, Stacey, Hill, Rebecca, Selby, Matthew, Lindsey, Janet, Rafiee, Gholamreza, Bailey, Simon, Williamson, Daniel, Clifford, Steve
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2018
主題:
Abstracts
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012067/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.482
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