The transcription factor CREM drives an inflammatory phenotype of T cells in oligoarticular juvenile idiopathic arthritis

BACKGROUND: Inflammatory effector T cells trigger inflammation despite increased numbers of Treg cells in the synovial joint of patients suffering from juvenile idiopathic arthritis (JIA). The cAMP response element (CREM)α is known to play a major role in regulation of T cells in SLE, colitis, and E...

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Détails bibliographiques
Publié dans:Pediatr Rheumatol Online J
Auteurs principaux: Ohl, Kim, Nickel, Helge, Moncrieffe, Halima, Klemm, Patricia, Scheufen, Anja, Föll, Dirk, Wixler, Viktor, Schippers, Angela, Wagner, Norbert, Wedderburn, Lucy R., Tenbrock, Klaus
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6011589/
https://ncbi.nlm.nih.gov/pubmed/29925386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12969-018-0253-x
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