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CREM Alpha Enhances IL-21 Production in T Cells In Vivo and In Vitro
The cAMP-responsive element modulator alpha (CREMα) plays a role in autoimmunity and, in particular, in systemic lupus erythematosus. CREMα negatively regulates IL-2 transcription and activates IL-17 expression by direct transcriptional mechanisms. To understand the role of CREM in autoimmunity, we...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5165720/ https://ncbi.nlm.nih.gov/pubmed/28066428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00618 |
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