LncGPR107 drives the self-renewal of liver tumor initiating cells and liver tumorigenesis through GPR107-dependent manner

BACKGROUND: With self-renewal and differentiation properties, liver tumor initiating cells (TICs) are the reasons for tumor initiation, metastasis and drug resistance. G protein coupled receptors (GPCR) are critical modulators in many physiological and pathological processes. While, their roles in l...

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Publicado en:J Exp Clin Cancer Res
Autores principales: Huang, Guanqun, Jiang, Hui, Lin, Ye, Xia, Wuzheng, Luo, Yuanwei, Wu, Yanpeng, Cai, Weilong, Zhou, Xinke, Jiang, Xianhan
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6011390/
https://ncbi.nlm.nih.gov/pubmed/29925408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0794-3
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