LncMAPK6 drives MAPK6 expression and liver TIC self-renewal

BACKGROUND: Liver tumor initiating cells (TICs) have self-renewal and differentiate capacities, and largely contribute to tumor initiation, metastasis and drug resistance. MAPK signaling is a critical pathway in many biological processes, while its role in liver TICs hasn’t been explored. METHODS: O...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Exp Clin Cancer Res
Main Authors: Huang, Guanqun, Jiang, Hui, He, Yueming, Lin, Ye, Xia, Wuzheng, Luo, Yuanwei, Liang, Min, Shi, Boyun, Zhou, Xinke, Jian, Zhixiang
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952634/
https://ncbi.nlm.nih.gov/pubmed/29764463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0770-y
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