A tightly controlled Src-YAP signaling axis determines therapeutic response to dasatinib in renal cell carcinoma

Over the past decade, therapies targeting the VEGF/VEGFR and mTOR pathways have served as the standard of care for the clinical management of renal cell carcinoma (RCC) patients. Albeit promising, these targeted drugs have attained only modest clinical benefits with limited prolonged progression-fre...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Sun, Jingya, Wang, Xin, Tang, Boyun, Liu, Hongchun, Zhang, Minmin, Wang, Yueqin, Ping, Fangfang, Ding, Jian, Shen, Aijun, Geng, Meiyu
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010995/
https://ncbi.nlm.nih.gov/pubmed/29930727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.23964
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