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NEFA‐induced ROS impaired insulin signalling through the JNK and p38MAPK pathways in non‐alcoholic steatohepatitis

The aim of this study was to investigate the changes in hepatic oxidative phosphorylation (OXPHOS) complexes (COs) in patients and cows with non‐alcoholic steatohepatitis (NASH) and to investigate the mechanism that links mitochondrial dysfunction and hepatic insulin resistance induced by non‐esteri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Gao, Wenwen, Du, Xiliang, Lei, Lin, Wang, Heyuan, Zhang, Min, Wang, Zhe, Li, Xiaobing, Liu, Guowen, Li, Xinwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010831/
https://ncbi.nlm.nih.gov/pubmed/29602237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13617
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