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Lenvatinib inhibits angiogenesis and tumor fibroblast growth factor signaling pathways in human hepatocellular carcinoma models

Unresectable hepatocellular carcinoma (uHCC) is one of the most lethal and prevalent cancers worldwide, and current systemic therapeutic options for uHCC are limited. Lenvatinib, a multiple receptor tyrosine kinase inhibitor targeting vascular endothelial growth factor receptors (VEGFRs) and fibrobl...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Matsuki, Masahiro, Hoshi, Taisuke, Yamamoto, Yuji, Ikemori‐Kawada, Megumi, Minoshima, Yukinori, Funahashi, Yasuhiro, Matsui, Junji
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010799/
https://ncbi.nlm.nih.gov/pubmed/29733511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1517
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