Multitargeting strategy using lenvatinib and golvatinib: Maximizing anti-angiogenesis activity in a preclinical cancer model

Almost all cancers show intrinsic and/or evasive resistance to vascular endothelial growth factor (VEGF) inhibitors by multiple mechanisms. Serum angiopoietin-2 (Ang2) level has been proposed as a potential biomarker of VEGF inhibitor response in several cancers. From these clinical observations, th...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Sci
Hauptverfasser: Nakazawa, Youya, Kawano, Satoshi, Matsui, Junji, Funahashi, Yasuhiro, Tohyama, Osamu, Muto, Hiroki, Nakagawa, Takayuki, Matsushima, Tomohiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2015
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399030/
https://ncbi.nlm.nih.gov/pubmed/25458359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12581
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