MYCN is a novel oncogenic target in adult B‐ALL that activates the Wnt/β‐catenin pathway by suppressing DKK3

Dickkopf‐3 (DKK3) is frequently down‐regulated by promoter hypermethylation and is closely associated with a poor prognosis in many cancers. Our previous studies have shown that miR‐708 down‐regulates DKK3 at the post‐transcriptional level in B‐ALL. However, whether transcriptional mechanisms lead t...

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Detalles Bibliográficos
Publicado en:J Cell Mol Med
Autores principales: Kong, Desheng, Zhao, Linlin, Sun, Lili, Fan, Shengjin, Li, Huibo, Zhao, Yanqiu, Guo, Zhibo, Lin, Leilei, Cui, Lin, Wang, Ke, Chen, Wenjia, Zhang, Yihui, Zhou, Jin, Li, Yinghua
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010754/
https://ncbi.nlm.nih.gov/pubmed/29673070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13644
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