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Estrogen Regulation of Dkk1 and Wnt/β-Catenin Signaling in Neurodegenerative Disease

17β-estradiol (E2 or estrogen) is an endogenous steroid hormone that is well known to exert neuroprotection. Along these lines, one mechanism through which E2 protects the hippocampus from cerebral ischemia is by preventing the post-ischemic elevation of Dkk1, a neurodegenerative factor that serves...

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Detalhes bibliográficos
Main Authors: Scott, Erin L., Brann, Darrell W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801191/
https://ncbi.nlm.nih.gov/pubmed/23261660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.12.015
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