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Long-Term Estrogen Deprivation Leads to Elevation of Dickkopf-1 and Dysregulation of Wnt/ -Catenin Signaling in Hippocampal CA1 Neurons
Surgically menopausal women incur a 2–5 fold increased risk for dementia and mortality from neurological diseases, but the mechanisms underlying these increased risks remain unclear. Previously, we demonstrated that after global cerebral ischemia (GCI), 17β-estradiol (E2 or estrogen) suppresses hipp...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3593754/ https://ncbi.nlm.nih.gov/pubmed/23178162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2012.11.004 |
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