Toll-Like Receptor 4 Triggering Promotes Cytosolic Routing of DC-SIGN-Targeted Antigens for Presentation on MHC Class I

DC-SIGN is an antigen uptake receptor expressed on dendritic cells (DCs) with specificity for glycans present on a broad variety of pathogens and is capable of directing its cargo to MHC-I and MHC-II pathways for the induction of CD8(+) and CD4(+) T cell responses, respectively. Therefore, DC-SIGN i...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Horrevorts, Sophie K., Duinkerken, Sanne, Bloem, Karien, Secades, Pablo, Kalay, Hakan, Musters, René J., van Vliet, Sandra J., García-Vallejo, Juan J., van Kooyk, Yvette
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010527/
https://ncbi.nlm.nih.gov/pubmed/29963041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01231
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi