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Glycan-based DC-SIGN targeting to enhance antigen cross-presentation in anticancer vaccines

In vivo dendritic-cell targeting constitutes a promising strategy for anticancer vaccination. Here, we discuss the usage of multivalent DC-SIGN-targeting glycan platforms that allow for the efficient routing of antigens to the endo-lysosomal pathway as well as to a yet uncharacterized cross-presenta...

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Detalhes bibliográficos
Main Authors: García-Vallejo, Juan J., Unger, Wendy W. J., Kalay, Hakan, van Kooyk, Yvette
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601176/
https://ncbi.nlm.nih.gov/pubmed/23525136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.23040
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