Rapid Effects of the Aromatase Inhibitor Fadrozole on Steroid Production and Gene Expression in the Ovary of Female Fathead Minnows (Pimephales promelas)

Cytochrome P450 aromatase catalyzes conversion of C19 androgens to C18 estrogens and is critical for normal reproduction in female vertebrates. Fadrozole is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish. However, little is known about the earl...

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Publicat a:Gen Comp Endocrinol
Autors principals: Schroeder, Anthony L., Ankley, Gerald T., Habib, Tanwir, Garcia-Reyero, Natalia, Escalon, Barbara L., Jensen, Kathleen M., Kahl, Michael D., Durhan, Elizabeth J., Makynen, Elizabeth A., Cavallin, Jenna E., Martinovic-Weigelt, Dalma, Perkins, Edward J., Villeneuve, Daniel L.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010346/
https://ncbi.nlm.nih.gov/pubmed/28736226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygcen.2017.07.022
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