Rapid Effects of the Aromatase Inhibitor Fadrozole on Steroid Production and Gene Expression in the Ovary of Female Fathead Minnows (Pimephales promelas)

Cytochrome P450 aromatase catalyzes conversion of C19 androgens to C18 estrogens and is critical for normal reproduction in female vertebrates. Fadrozole is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish. However, little is known about the earl...

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Detalhes bibliográficos
Publicado no:Gen Comp Endocrinol
Main Authors: Schroeder, Anthony L., Ankley, Gerald T., Habib, Tanwir, Garcia-Reyero, Natalia, Escalon, Barbara L., Jensen, Kathleen M., Kahl, Michael D., Durhan, Elizabeth J., Makynen, Elizabeth A., Cavallin, Jenna E., Martinovic-Weigelt, Dalma, Perkins, Edward J., Villeneuve, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010346/
https://ncbi.nlm.nih.gov/pubmed/28736226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygcen.2017.07.022
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