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Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM
CD40 is a member of the tumor necrosis factor receptor superfamily, expressed on a wide range of cell types including B cells, macrophages, and dendritic cells. CD40 is the receptor for CD40 ligand (CD40L), a molecule predominantly expressed by activated CD4(+) T cells. CD40/CD40L interaction induce...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC60102/ https://ncbi.nlm.nih.gov/pubmed/11675497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.221456898 |
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