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A Chemotherapy-only Regimen of Busulfan, Melphalan, and Fludarabine, and Rabbit ATG followed by Allogeneic T-cell Depleted Hematopoietic Stem Cell Transplants for the Treatment of Myeloid Malignancies

We sought to develop a myeloablative chemotherapeutic regimen to secure consistent engraftment of T-cell depleted (TCD) hematopoietic stem cell transplants (HSCT) without the need for total body irradiation, thereby reducing toxicity, while maintaining low rates of GvHD and without increasing relaps...

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Detalhes bibliográficos
Publicado no:Biol Blood Marrow Transplant
Main Authors: Spitzer, Barbara, Jakubowski, Ann A., Papadopoulos, Esperanza B., Fuller, Kirsten, Hilden, Patrick D., Young, James W., Barker, Juliet, Koehne, Guenther, Perales, Miguel-Angel, Hsu, Katharine C., van den Brink, Marcel R.M., Kernan, Nancy A, Prockop, Susan E., Scaradavou, Andromachi, Castro-Malaspina, Hugo, O'Reilly, Richard J., Boulad, Farid
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010191/
https://ncbi.nlm.nih.gov/pubmed/28711727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2017.07.004
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