Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma

BACKGROUND: Diffuse large B-cell lymphomas (DLBCLs) are phenotypically and genetically heterogeneous. Gene-expression profiling has identified subgroups of DLBCL (activated B-cell–like [ABC], germinal-center B-cell–like [GCB], and unclassified) according to cell of origin that are associated with a...

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Gepubliceerd in:N Engl J Med
Hoofdauteurs: Schmitz, R., Wright, G.W., Huang, D.W., Johnson, C.A., Phelan, J.D., Wang, J.Q., Roulland, S., Kasbekar, M., Young, R.M., Shaffer, A.L., Hodson, D.J., Xiao, W., Yu, X., Yang, Y., Zhao, H., Xu, W., Liu, X., Zhou, B., Du, W., Chan, W.C., Jaffe, E.S., Gascoyne, R.D., Connors, J.M., Campo, E., Lopez-Guillermo, A., Rosenwald, A., Ott, G., Delabie, J., Rimsza, L.M., Wei, K. Tay Kuang, Zelenetz, A.D., Leonard, J.P., Bartlett, N.L., Tran, B., Shetty, J., Zhao, Y., Soppet, D.R., Pittaluga, S., Wilson, W.H., Staudt, L.M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010183/
https://ncbi.nlm.nih.gov/pubmed/29641966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1801445
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