Multicomponent synthesis of some new (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-dithiocarbamates and their in vitro anti-proliferative activity against CaSki, MDA-MB-231 and SK-Lu-1 tumour cells as apoptosis inducing agents without necrosis

Identification of a new class of antitumor agent capable to induce apoptosis without triggering necrotic cell death event is challenging. The present communication describes the multicomponent synthesis of seven new (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-dithiocarbamates and their in vitro antiproli...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Laskar, Sujay, Sánchez-Sánchez, Luis, López-Ortiz, Manuel, López-Muñoz, Hugo, Escobar-Sánchez, María L., Sánchez, Arturo T., Regla, Ignacio
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010139/
https://ncbi.nlm.nih.gov/pubmed/28868930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1363197
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