N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation

Synthetic or natural carbazole derivatives constitute an interesting class of heterocycles, which showed several pharmaceutical properties and occupied a promising place as antitumour tools in preclinical studies. They target several cellular key-points, e.g. DNA and Topoisomerases I and II. The mos...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Sinicropi, Maria Stefania, Iacopetta, Domenico, Rosano, Camillo, Randino, Rosario, Caruso, Anna, Saturnino, Carmela, Muià, Noemi, Ceramella, Jessica, Puoci, Francesco, Rodriquez, Manuela, Longo, Pasquale, Plutino, Maria Rosaria
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010102/
https://ncbi.nlm.nih.gov/pubmed/29383954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1419216
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