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Synthesis of sericin-based conjugates by click chemistry: enhancement of sunitinib bioavailability and cell membrane permeation

Sericin is a natural protein that has been used in biomedical and pharmaceutical fields as raw material for polypeptide-based drug delivery systems (DDSs). In this paper, it has been employed as pharmaceutical biopolymer for the production of sunitinib–polypeptide conjugate. The synthesis has been c...

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Bibliografische gegevens
Gepubliceerd in:Drug Deliv
Hoofdauteurs: Scrivano, Luca, Iacopetta, Domenico, Sinicropi, Maria Stefania, Saturnino, Carmela, Longo, Pasquale, Parisi, Ortensia Ilaria, Puoci, Francesco
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240991/
https://ncbi.nlm.nih.gov/pubmed/28181828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2016.1267822
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