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Inhibition of protein tyrosine phosphatase (PTP1B) and α-glucosidase by geranylated flavonoids from Paulownia tomentosa

Protein tyrosine phosphatase 1B (PTP1B) and α-glucosidase are important targets to treat obesity and diabetes, due to their deep correlation with insulin and leptin signalling, and glucose regulation. The methanol extract of Paulownia tomentosa fruits showed potent inhibition against both enzymes. P...

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Bibliografske podrobnosti
izdano v:J Enzyme Inhib Med Chem
Main Authors: Song, Yeong Hun, Uddin, Zia, Jin, Young Min, Li, Zuopeng, Curtis-Long, Marcus John, Kim, Kwang Dong, Cho, Jung Keun, Park, Ki Hun
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010085/
https://ncbi.nlm.nih.gov/pubmed/28933230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1368502
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