Discovery of curcumin inspired sulfonamide derivatives as a new class of carbonic anhydrase isoforms I, II, IX, and XII inhibitors

A series of curcumin inspired sulfonamide derivatives was prepared from various chalcones and 4-sulfamoyl benzaldehyde via Claisen–Schmidt condensation. All new compounds were assayed as inhibitors of four human isoforms of the metalloenzyme carbonic anhydrase (hCA, EC 4.2.1.1) isoforms hCA I, II, I...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Ramya, P. V. Sri, Angapelly, Srinivas, Angeli, Andrea, Digwal, Chander Singh, Arifuddin, Mohammed, Babu, Bathini Nagendra, Supuran, Claudiu T., Kamal, Ahmed
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010064/
https://ncbi.nlm.nih.gov/pubmed/28965419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1380638
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados