A novel series of pyrazole-platinum(II) complexes as potential anti-cancer agents that induce cell cycle arrest and apoptosis in breast cancer cells

Six novel compounds of platinum(II) with pyrazole derivatives PtPz1–PtPz6 were synthesised and characterised (PtPz1 - [Pt(2)N-hydroksymethyl-3,5-dimethylpyrazole(4)(berenil)(2)]Cl(4); PtPz2 - [Pt(2)3,5-dimethylpyrazole(4)(berenil)(2)]Cl(4); PtPz3 - [Pt(2)3,4-dimethylpyrazole(4)(berenil)(2)]Cl(4); Pt...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Czarnomysy, Robert, Surażyński, Arkadiusz, Muszynska, Anna, Gornowicz, Agnieszka, Bielawska, Anna, Bielawski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009892/
https://ncbi.nlm.nih.gov/pubmed/29862867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1471687
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