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The molecular mechanism of anticancer action of novel octahydropyrazino[2,1-a:5,4-a′]diisoquinoline derivatives in human gastric cancer cells

Objective The aim of the current study was to examine the anticancer activity and the detailed mechanism of novel diisoquinoline derivatives in human gastric cancer cells (AGS). Methods The viability of AGS cells was measured by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assa...

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Detalhes bibliográficos
Publicado no:Invest New Drugs
Main Authors: Pawłowska, Natalia, Gornowicz, Agnieszka, Bielawska, Anna, Surażyński, Arkadiusz, Szymanowska, Anna, Czarnomysy, Robert, Bielawski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6244973/
https://ncbi.nlm.nih.gov/pubmed/29549610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-018-0584-y
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