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A general strategy for direct, enzyme-catalyzed conjugation of functional compounds to DNA
The methyltransferase enzymes can be applied to deliver a range of modifications to pre-determined sites on large DNA molecules with exceptional specificity and efficiency. To date, however, a limited number of modifications have been delivered in this way because of the complex chemical synthesis t...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6009647/ https://ncbi.nlm.nih.gov/pubmed/29546351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky184 |
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