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A general strategy for direct, enzyme-catalyzed conjugation of functional compounds to DNA

The methyltransferase enzymes can be applied to deliver a range of modifications to pre-determined sites on large DNA molecules with exceptional specificity and efficiency. To date, however, a limited number of modifications have been delivered in this way because of the complex chemical synthesis t...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Deen, Jochem, Wang, Su, Van Snick, Sven, Leen, Volker, Janssen, Kris, Hofkens, Johan, Neely, Robert K
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009647/
https://ncbi.nlm.nih.gov/pubmed/29546351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky184
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