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Crystal Structures of Tcl1 Family Oncoproteins and Their Conserved Surface Features
Members of the TCL1 family of oncogenes are abnormally expressed in mature T-cell leukemias and B-cell lymphomas. The proteins are involved in the coactivation of protein kinase B (Akt/PKB), a key intracellular kinase. The sequences and crystal structures of three Tcl1 proteins were analyzed in orde...
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| Pubblicato in: | ScientificWorldJournal |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
TheScientificWorldJOURNAL
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6009430/ https://ncbi.nlm.nih.gov/pubmed/12920316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/tsw.2002.826 |
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