Dehydrocorydaline attenuates bone cancer pain by shifting microglial M1/M2 polarization toward the M2 phenotype

Bone cancer pain remains a major challenge in patients with primary or metastatic bone cancer due to a lack of understanding the mechanisms. Previous studies have revealed the two distinct functional polarization states of microglia (classically activated M1 and alternatively activated M2) in the sp...

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Vydáno v:Mol Pain
Hlavní autoři: Huo, Wenwen, Zhang, Ying, Liu, Yue, Lei, Yishan, Sun, Rao, Zhang, Wei, Huang, Yulin, Mao, Yanting, Wang, Chenchen, Ma, Zhengliang, Gu, Xiaoping
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009085/
https://ncbi.nlm.nih.gov/pubmed/29882480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806918781733
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