Astaxanthin acts via LRP-1 to inhibit inflammation and reverse lipopolysaccharide-induced M1/M2 polarization of microglial cells

Microglia become activated during neuroinflammation and produce neurotoxic and neurotrophic factors, depending on whether they acquire M1 proinflammatory or M2 anti-inflammatory phenotypes. Astaxanthin (ATX), a natural carotenoid, has anti-inflammatory and neuroprotective effects. We investigated wh...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wen, Xiaojun, Xiao, Lijiao, Zhong, Zhuoyan, Wang, Limin, Li, Ze, Pan, Xiaoping, Liu, Zhonglin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper: Gerotarget (Focus on Aging)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642485/
https://ncbi.nlm.nih.gov/pubmed/29050210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20628
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