Interleukin-17A Promotes Parietal Cell Atrophy by Inducing Apoptosis

BACKGROUND & AIMS: Atrophic gastritis caused by chronic inflammation in the gastric mucosa leads to the loss of gastric glandular cells, including acid-secreting parietal cells. Parietal cell atrophy in a setting of chronic inflammation induces spasmolytic polypeptide expressing metaplasia, a cr...

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Bibliografiske detaljer
Udgivet i:Cell Mol Gastroenterol Hepatol
Main Authors: Bockerstett, Kevin A., Osaki, Luciana H., Petersen, Christine P., Cai, Catherine W., Wong, Chun Fung, Nguyen, Thanh-Long M., Ford, Eric L., Hoft, Daniel F., Mills, Jason C., Goldenring, James R., DiPaolo, Richard J.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009015/
https://ncbi.nlm.nih.gov/pubmed/29930985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.12.012
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