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Targeted Apoptosis of Parietal Cells is Insufficient to Induce Metaplasia in Stomach

Parietal cell atrophy is considered to cause metaplasia in the stomach. We developed mice that express the diphtheria toxin receptor specifically in parietal cells to induce their death, and found this to increase proliferation in the normal stem cell zone and neck but not to cause metaplastic repro...

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Publicado en:Gastroenterology
Autores principales: Burclaff, Joseph, Osaki, Luciana H., Liu, Dengqun, Goldenring, James R., Mills, Jason C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391042/
https://ncbi.nlm.nih.gov/pubmed/27932312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2016.12.001
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