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Targeted Apoptosis of Parietal Cells is Insufficient to Induce Metaplasia in Stomach

Parietal cell atrophy is considered to cause metaplasia in the stomach. We developed mice that express the diphtheria toxin receptor specifically in parietal cells to induce their death, and found this to increase proliferation in the normal stem cell zone and neck but not to cause metaplastic repro...

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Detaylı Bibliyografya
Yayımlandı:Gastroenterology
Asıl Yazarlar: Burclaff, Joseph, Osaki, Luciana H., Liu, Dengqun, Goldenring, James R., Mills, Jason C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391042/
https://ncbi.nlm.nih.gov/pubmed/27932312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2016.12.001
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