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Targeted Apoptosis of Parietal Cells is Insufficient to Induce Metaplasia in Stomach

Parietal cell atrophy is considered to cause metaplasia in the stomach. We developed mice that express the diphtheria toxin receptor specifically in parietal cells to induce their death, and found this to increase proliferation in the normal stem cell zone and neck but not to cause metaplastic repro...

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Detalhes bibliográficos
Publicado no:Gastroenterology
Main Authors: Burclaff, Joseph, Osaki, Luciana H., Liu, Dengqun, Goldenring, James R., Mills, Jason C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391042/
https://ncbi.nlm.nih.gov/pubmed/27932312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2016.12.001
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