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Targeted Apoptosis of Parietal Cells is Insufficient to Induce Metaplasia in Stomach
Parietal cell atrophy is considered to cause metaplasia in the stomach. We developed mice that express the diphtheria toxin receptor specifically in parietal cells to induce their death, and found this to increase proliferation in the normal stem cell zone and neck but not to cause metaplastic repro...
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| Gepubliceerd in: | Gastroenterology |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5391042/ https://ncbi.nlm.nih.gov/pubmed/27932312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2016.12.001 |
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