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Different Expression Levels of Human Mutant Ubiquitin B(+1) (UBB(+1)) Can Modify Chronological Lifespan or Stress Resistance of Saccharomyces cerevisiae
The ubiquitin-proteasome system (UPS) is the main pathway responsible for the degradation of misfolded proteins, and its dysregulation has been implicated in several neurodegenerative diseases, including Alzheimer’s disease (AD). UBB(+1), a mutant variant of ubiquitin B, was found to accumulate in n...
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| Publicado no: | Front Mol Neurosci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6008557/ https://ncbi.nlm.nih.gov/pubmed/29950972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00200 |
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