Different Expression Levels of Human Mutant Ubiquitin B(+1) (UBB(+1)) Can Modify Chronological Lifespan or Stress Resistance of Saccharomyces cerevisiae

The ubiquitin-proteasome system (UPS) is the main pathway responsible for the degradation of misfolded proteins, and its dysregulation has been implicated in several neurodegenerative diseases, including Alzheimer’s disease (AD). UBB(+1), a mutant variant of ubiquitin B, was found to accumulate in n...

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Publicat a:Front Mol Neurosci
Autors principals: Muñoz-Arellano, Ana Joyce, Chen, Xin, Molt, Andrea, Meza, Eugenio, Petranovic, Dina
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008557/
https://ncbi.nlm.nih.gov/pubmed/29950972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00200
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