Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer

BACKGROUND: Substantial evidence supports an association between use of menopausal hormone therapy and decreased colorectal cancer (CRC) risk, indicating a role of exogenous sex hormones in CRC development. However, findings on endogenous oestrogen exposure and CRC are inconsistent. METHODS: We used...

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Publicat a:Br J Cancer
Autors principals: Neumeyer, Sonja, Banbury, Barbara L., Arndt, Volker, Berndt, Sonja I., Bezieau, Stephane, Bien, Stephanie A., Buchanan, Dan D., Butterbach, Katja, Caan, Bette J., Campbell, Peter T., Casey, Graham, Chan, Andrew T., Chanock, Stephen J., Dai, James Y., Gallinger, Steven, Giovannucci, Edward L., Giles, Graham G., Grady, William M., Hampe, Jochen, Hoffmeister, Michael, Hopper, John L., Hsu, Li, Jenkins, Mark A., Joshi, Amit, Larsson, Susanna C., Le Marchand, Loic, Lindblom, Annika, Moreno, Victor, Lemire, Mathieu, Li, Li, Lin, Yi, Offit, Kenneth, Newcomb, Polly A., Pharaoh, Paul D., Potter, John D., Qi, Lihong, Rennert, Gad, Schafmayer, Clemens, Schoen, Robert E., Slattery, Martha L., Song, Mingyang, Ulrich, Cornelia M., Win, Aung K., White, Emily, Wolk, Alicja, Woods, Michael O., Wu, Anna H., Gruber, Stephen B., Brenner, Hermann, Peters, Ulrike, Chang-Claude, Jenny
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008474/
https://ncbi.nlm.nih.gov/pubmed/29795306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0108-8
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