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Blocking CXCL1-dependent neutrophil recruitment prevents immune damage and reduces pulmonary bacterial infection after inhalation injury

Smoke inhalation associated with structural fires, wildfires, or explosions leads to lung injury, for which innovative and clinically relevant animal models are needed to develop effective therapeutics. We have previously reported that damage-associated molecular patterns (DAMPs) and anti-inflammato...

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Publicat a:Am J Physiol Lung Cell Mol Physiol
Autors principals: Dunn, Julia L. M., Kartchner, Laurel B., Stepp, Wesley H., Glenn, Lindsey I., Malfitano, Madison M., Jones, Samuel W., Doerschuk, Claire M., Maile, Robert, Cairns, Bruce A.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008131/
https://ncbi.nlm.nih.gov/pubmed/29368547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00272.2017
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