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Mitochondria-targeted antioxidant therapy with MitoQ ameliorates aortic stiffening in old mice

Aortic stiffening is a major independent risk factor for cardiovascular diseases, cognitive dysfunction, and other chronic disorders of aging. Mitochondria-derived reactive oxygen species are a key source of arterial oxidative stress, which may contribute to arterial stiffening by promoting adverse...

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Dettagli Bibliografici
Pubblicato in:J Appl Physiol (1985)
Autori principali: Gioscia-Ryan, Rachel A., Battson, Micah L., Cuevas, Lauren M., Eng, Jason S., Murphy, Michael P., Seals, Douglas R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008077/
https://ncbi.nlm.nih.gov/pubmed/29074712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00670.2017
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