Mitochondria-targeted antioxidant (MitoQ) ameliorates age-related arterial endothelial dysfunction in mice

Age-related arterial endothelial dysfunction, a key antecedent of the development of cardiovascular disease (CVD), is largely caused by a reduction in nitric oxide (NO) bioavailability as a consequence of oxidative stress. Mitochondria are a major source and target of vascular oxidative stress when...

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Bibliografiset tiedot
Päätekijät: Gioscia-Ryan, Rachel A, LaRocca, Thomas J, Sindler, Amy L, Zigler, Melanie C, Murphy, Michael P, Seals, Douglas R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Science Inc 2014
Aiheet:
Cardiovascular
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080937/
https://ncbi.nlm.nih.gov/pubmed/24665093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.268680
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