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Extracellular Regulated Kinases: Signaling from Ras to ERK Substrates to Control Biological Outcomes

The extracellular regulated kinases ERK1 and ERK2 are evolutionarily conserved, ubiquitous serine-threonine kinases that are involved in regulating cellular signaling in both normal and pathological conditions. Their expression is critical for development and their hyperactivation is a major factor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Adv Cancer Res
1. Verfasser: Eblen, Scott T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007982/
https://ncbi.nlm.nih.gov/pubmed/29551131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.acr.2018.02.004
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