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An (18)F-Labeled Poly(ADP-ribose) Polymerase Positron Emission Tomography Imaging Agent

[Image: see text] Poly(ADP-ribose) polymerase (PARP) is involved in repair of DNA breaks and is over-expressed in a wide variety of tumors, making PARP an attractive biomarker for positron emission tomography (PET) and single photon emission computed tomography imaging. Consequently, over the past d...

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Détails bibliographiques
Publié dans:J Med Chem
Auteurs principaux: Zmuda, Filip, Blair, Adele, Liuzzi, Maria Clara, Malviya, Gaurav, Chalmers, Anthony J., Lewis, David, Sutherland, Andrew, Pimlott, Sally L.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2018
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007963/
https://ncbi.nlm.nih.gov/pubmed/29630818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.8b00138
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