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AUTOIMMUNITY TO RNA POLYMERASE II IS FOCUSED AT THE CARBOXYL TERMINAL DOMAIN OF THE LARGE SUBUNIT

OBJECTIVE: Previous studies have demonstrated antibodies to the large (220 kd) polypeptide subunit of RNA polymerase II (Pol II) in sera from certain patients with scleroderma. In the present study, we sought to identify the autoantigenic region on this polypeptide. METHODS: A recombinant fusion pro...

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Detalles Bibliográficos
Publicado en:Arthritis Rheum
Main Authors: HIRAKATA, MICHITO, KANUNGO, JYOTSHNA, SUWA, AKIRA, TAKEDA, YOSHIHIKO, CRAFT, JOE, HARDIN, JOHN A.
Formato: Artigo
Idioma:Inglês
Publicado: 1996
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007873/
https://ncbi.nlm.nih.gov/pubmed/8912511
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