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Identification of autoantibodies to RNA polymerase II. Occurrence in systemic sclerosis and association with autoantibodies to RNA polymerases I and III.

In this study, autoantibodies to RNA polymerase II from sera of patients with systemic sclerosis have been identified and characterized. These antibodies immunoprecipitated polypeptides of 220 kD (IIA) and 145 kD (IIC), the two largest subunits of RNA polymerase II, and bound both subunits in immuno...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Hirakata, M, Okano, Y, Pati, U, Suwa, A, Medsger, T A, Hardin, J A, Craft, J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 1993
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443330/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8390487/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116505
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